Inflammatory Bowel Syndrome
With this term inflammatory bowel syndrome, perhaps not very correct, but certainly of practical use, are designated ulcerative colitis and Crohn’s disease, including many clinical conditions for which they are associated.
Aspects peculiar differences between ulcerative colitis and Crohn’s disease.
Ulcerative colitis is an inflammatory disease of the lining of the rectum and colon. The rectum is virtually concerned and inflammation from here you can still extend proximally to the rectum, also including the sigmoid or ascending colon (left section of the colon). In contrast Crohn’s disease affects, typically, all layers of the intestinal wall, involving the entire digestive tract, with a continuous distribution of the lesions. The small intestine is most frequently involved, particularly the terminal ileum, but it is also common Crohn’s colitis. Rarely, Crohn’s disease can affect the stomach and esophagus. In most cases, however, a definite diagnosis is not possible, it remains a 10% of subjects with a picture in the balance between the two diseases, where it is impossible to make a diagnosis: thus we speak generally of “inflammatory disease bowel. ”
In particular we have the following entities nosographic.
Ulcerative colitis (R.C.U).
Symptoms: subjects emit diarrheal feces and blood in the feces. If the inflammation of the rectum the stool is formed, if the colon is concerned there will be bloody diarrhea due to decreased absorption of water and electrolytes by the inflamed mucosa. Patients complain of cramps in lower abdomen that may temporarily find relief in the evacuation, may be a sense of “weight” to the rectum, a kind of urge to evacuate (rectal urgency).
Course and events: the disease onset in childhood or sometimes well into adulthood. The course is characterized by exacerbations of symptoms with complete or partial remission between episodes and more. In about 5-10% of cases there may be a single episode followed by symptoms for ten years. In other cases, the symptoms and the course is continuous, in others, can be fulminant and imposes emergency proctocolectomy. When these inflammatory bowel disease affecting the child, growth disturbance appear, so in these cases the diagnosis should be made early and treatment is imperative. The disease, however, associated with other intestinal manifestations, such as joint inflammation (arthritis, peripheral, ankylosing spondylitis), skin (erythema nodosum, pyoderma gangrenosum), (see UC and ankylosing spondylitis), eye (iritis and conjunctivitis) , liver (fatty liver, chronic active hepatitis, sclerosing cholangitis, bile duct cancer), kidney (pyelonephritis), amyloidosis.
Inflammatory Bowel Syndrome
Physical examination. Patients may have anemia, due to the loss of red blood cells, is the situational malabsorption, and there is dehydration and hypovolemia, tachycardia, fever, elevated erythrocyte sedimentation rate, leukocytosis, pain intensity medium-small bowel, with abdominal distension and signs of (Blumberg); exploration of the rectum has stools mixed with blood.
Diagnosis:
Double-contrast barium enema: never run if there is an acute clinical situation, because it can give toxic megacolon, and because the preparation is always energetic with cathartic avoided in acute cases, better electrolyte solutions administered orally. Nevertheless, the double-contrast barium enema is an ideal method for cost and investigation. It shows a granularity of the mucosa, loss of austrature (ie the design of the colon, which then appears as a tube, sometimes there are areas of stenosis, small (cancer?), Sometimes even the ileum is affected (terminal ileitis, Crohn’s ?).
Inflammatory Bowel Syndrome
Rettosigmoidocolonscopia. The mucosa of the rectum endoscopic examination appears uneven and granulomatous, crumbly and easy to bleed the passage of the instrument, there may be ulcerated areas and pseudopolyps. Profit mucosa biopsied for histologic diagnosis: biopsy highlight: infiltration of the mucosa by inflammatory cells, flattening of epithelial cells of the mucosal surface, mucosal thinning, distortion of crypts, which are branched, cryptic abscesses.
The stool test shows:
leukocytes in the stools, the absence of parasites (amoebas, giardia, etc.),
Stool cultures for escluderecoliti infectious bacterial pathogens (Campylobacter jejuni, Clostridium difficile) Inflammatory Bowel Syndrome
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Tagged with: bowel syndrome • inflammatory bowel syndrome • irritable bowl syndrome • treatment irritable bowel syndrome
Filed under: Digestive Health • IBS
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